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Can You Take Melatonin Every Night? What to Know

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May 9, 2025

Can You Take Melatonin Every Night? What to Know

Medically reviewed by: 

Dr. Shiyan Yeo

School of Medical Sciences, University of Manchester

Melatonin has become incredibly popular as a sleep supplement. It feels more natural than sleeping medication, yet more effective than other supplements. Walk into any pharmacy or grocery store, and you'll find countless options for supplemental melatonin - both brands and dosage. But if you're struggling with sleep consistently, you might wonder, "Can I really take this every single night?" At the end of the day, it’s still something that is chemically altering your body. 

It's a common question, and the answer is a bit more nuanced than a simple yes or no. While supplemental melatonin is relatively safe for short-term use, taking it every night or long-term use warrants a closer look at how it impacts your sleep-wake cycles and other melatonin side effects. We will break down here what you need to know.

What is Melatonin?

First off, melatonin isn't like a strong sleeping pill that just knocks you out. It's actually something your own body makes! Your brain (specifically a tiny spot called the pineal gland) executes a timed production of melatonin when it gets dark. Its main job? To send a signal that says, "Hey body, it's nighttime! Start winding down and get ready for sleep." It's a key player in keeping your internal clock, your circadian rhythm, running smoothly.

Think of this natural melatonin production as your body's natural signal for bedtime, not a sedative that forces you to sleep. Once your brain starts signaling the creation of melatonin, your body starts kicking off other processes to get you to fall asleep. 

Where Melatonin Can Actually Be Pretty Helpful (Usually Short-Term)

Melatonin supplements tend to work best when you need to reset or adjust your body clock because it's out of whack. This is why doctors or sleep experts might suggest it for things like:

  • Seriously Bad Jet Lag: When you've hopped across time zones and your body clock is totally confused, melatonin for jet lag is often recommended as a short-term cure.
  • Shift Work Struggles: If you're working nights and sleeping during the day, this can cause you to have delayed sleep-wake phase disorder. Sleep aids such as melatonin can help signal sleep time even when the sun is out and you’re getting light exposure. 
  • Delayed Sleep Phase (Being a Total Night Owl): For people whose natural rhythm is just wired to go to bed way, way later than most, it can help nudge that timing earlier regardless of the time of day.

For these specific situations, using it for a short time can really help your body get back on schedule and into a deep sleep cycle.

Be Careful However About Taking It Every Night

This is where caution is needed. While melatonin is primarily viewed as a natural health product and not considered addictive in the way sleep medications can be, you should still consider these areas and potential effects of melatonin:

  1. It Doesn't Fix the Root Cause of Insomnia: Chronic insomnia is often caused by underlying issues like stress, anxiety, poor sleep habits, diet, or even undiagnosed sleep disorders. Melatonin doesn't address these core problems.
  2. Potential Side Effects: While generally well-tolerated, some people experience side effects like vivid dreams, daytime grogginess, headaches, dizziness, or nausea.
  3. Masking a Real Disorder: Relying on melatonin every night might prevent you from seeking help for an actual primary sleep disorder (like sleep apnea, restless legs syndrome, or chronic insomnia) that requires proper diagnosis and treatment.
  4. Unknown Long-Term Effects: Because melatonin supplements are often classified as dietary supplements rather than drugs, they don't undergo the same rigorous testing for long-term safety and efficacy. And because they are a supplement, we do not have extensive science studies on the effects of taking it every single night for a long period of time. There have been studies about how it affects adolescents, pregnant women, breastfeeding, and more. 
  5. Dosage Consistency Issues: As a supplement, the actual dose of melatonin in a pill can sometimes vary from what's listed on the label, making consistent dosing tricky. The variability of melatonin content by brand is a concerning issue - make sure you verify that the company has a reputable brand and always look at the doses of melatonin listed on the label - generally taking a 3-5mg dose of melatonin at night is considered safe. Taking higher doses of melatonin should be treated with caution. 
  6. Potential Interactions: Melatonin can interact with certain medications, including blood thinners, diabetes medications, immunosuppressants, and contraceptives, regardless of the melatonin dosages. Always consult with your healthcare provider on any melatonin sleep aids and their respective melatonin levels if you have other health conditions, such as seizure disorders or autoimmune disorders, and especially if you are on blood pressure medications or other prescription medications. 

How Many Nights Can I Take Melatonin? 

Melatonin is generally considered safe for short-term use, and many people take it for a few days to a few weeks to help adjust their sleep schedule. We would recommend not taking it for more than a month as it’s not meant for long-term nightly use without medical guidance. Taking melatonin regularly for extended periods may not address the underlying cause of sleep problems and could affect your natural sleep-wake cycle. It’s best to use melatonin as a temporary sleep aid and consult a healthcare provider if you need ongoing support.

The Takeaway: Generally Not a Long-Term, Every-Night Solution

Most sleep experts and health care providers (including researchers at the National Center for Complementary and Integrative Health) agree that for chronic, nightly sleep problems, melatonin is not intended as a first-line or long-term daily treatment. It's best used for adjusting to timing issues or for very short-term relief under guidance.

Is Melatonin The Best Supplement For Sleep? 

While melatonin can be helpful for certain sleep issues, like jet lag or shifting sleep schedules, it’s not always the most effective solution for chronic insomnia or other sleep disorders. Its benefits are mostly for regulating sleep timing rather than improving overall sleep quality or duration. For many people, addressing lifestyle factors or exploring other evidence-based treatments may be more effective than relying solely on melatonin.

What Should You Do Instead for Regular Sleep Issues?

If you consistently struggle to sleep, the most effective approach is to:

  • Focus on Sleep Hygiene: Establish a regular sleep schedule (even on weekends), create a relaxing bedtime routine and start the routine a few hours before bedtime, optimize your bedroom environment (dark, quiet, cool), limit caffeine and alcohol, and limit screen time before bed.
  • Consider Cognitive Behavioral Therapy for Insomnia (CBT-I): This is considered the gold standard treatment for chronic insomnia. It's a behavioral therapy that helps you identify and change thoughts and behaviors that negatively affect your ability to sleep. CBTI helps to rewire your brain such that you build a stronger bed-sleep connection and this also influences your natural melatonin production to improve your sleep efficiency. Talk to us at Sleep Reset for our CBTI-based insomnia program that has helped hundreds of thousands of people already get restful sleep. 
  • Talk to a Healthcare Professional: This is the most important step. A doctor can help identify the root cause of your sleep problems, recommend appropriate treatments (which might include short-term melatonin use or other options), and ensure it won't interact with other health conditions or medications you have.

Final Recommendation For Melatonin

In summary, while taking melatonin occasionally for time zone adjustments or temporary schedule changes is likely fine for most healthy adults, taking it every night for chronic sleep problems is generally not recommended without medical supervision. It's far better to work on fundamental sleep habits and consult a doctor to uncover and treat any underlying issues.

Dr. Shiyan Yeo

Dr. Shiyan Yeo is a medical doctor with over a decade of experience treating patients with chronic conditions. She graduated from the University of Manchester with a Bachelor of Medicine and Surgery (MBChB UK) and spent several years working at the National Health Service (NHS) in the United Kingdom, several Singapore government hospitals, and private functional medicine hospitals. Dr. Ooi specializes in root cause analysis, addressing hormonal, gut health, and lifestyle factors to treat chronic conditions. Drawing from her own experiences, she is dedicated to empowering others to optimize their health. She loves traveling, exploring nature, and spending quality time with family and friends.